Search Results - Genetics

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Targeting MBLAC1 for the Treatment of Substance Abuse
Through a vast array of experiments, FAU researchers have discovered that ceftriaxone (CEF) is a high affinity binding partner with MBLAC1 and may be responsible for its neuroprotective properties. Mice were genetically modified to lack the MBLAC1 gene and compared to normal mice after the administration of cocaine. The mice lacking MBLAC1 had sign...
Published: 11/8/2018   |   Inventor(s): Randy Blakely, Maureen Hahn
Keywords(s):  
Category(s): Genetics
Mouse Model to Study the Psychostimulant-Ceftriaxone Axis
FAU researchers have effectively knocked out the MBLAC1 gene in mice. It has been shown that the human MBLAC1 protein binds directly to ceftriaxone (CEF), which is known to interfere with the activity and addictive properties of several commonly abused drugs, potentially curbing drug-seeking behavior. Thus, mice given cocaine are extremely hyperact...
Published: 11/8/2018   |   Inventor(s): Randy Blakely
Keywords(s):  
Category(s): Genetics
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