Use Of Manzamine Compounds In Anti-Cancer Therapeutic Regimens

Description:

Manzamine compounds have been discovered to decrease cell dissociation and cell migration associated with the metastatic potential of cancer cells and a restoration of cancer cell susceptibility to agents, such as TRAIL, which can induce apoptosis. Specifically, Manzamine A has a formerly unrecognized utility in both blocking tumor cell invasion and tumor metastasis as well in restoring cancer cell susceptibility to standard chemotherapeutic agents which induce apoptosis and, therefore, has utility in treating cancer.

Patent Information:
Category(s):
Oncology
Drug Discovery
For Information, Contact:
Dana Vouglitois
Florida Atlantic University
dvouglitois@fau.edu
Inventors:
Amy Wright
Ester Guzman
Jacob Johnson
Keywords:
HBOI
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